HOWARU® Shape Danish Weight-Management Probiotic (B. lactis B420™)

INGREDIENT PROFILE

What this ingredient is documented for

Origin

Denmark

Developer

International Flavors & Fragrances Inc. (IFF / Danisco®)

• Weight-management strain Bifidobacterium animalis ssp. lactis B420™ from Danisco® (now IFF), at 10 billion CFU per day — alone or combined with 12 g of the prebiotic fiber Litesse® Ultra™ (polydextrose)
• Six-month, four-center, double-blind placebo-controlled human trial: 4.5% less total body fat mass, 6.7% less trunk fat and a 2.6 cm smaller waist, with no change to diet or exercise (per-protocol vs. placebo)
• Fat loss concentrated in the trunk — 4.7% less waist fat mass versus only 1.6% less hip fat mass, a region-selective effect
• Mechanistic work shows improved intestinal epithelial barrier function and higher relative abundance of Akkermansia muciniphila, linked to better metabolic health and anti-inflammatory activity
• Backed by 90+ scientific publications and 30+ clinical trial papers; stimulant-free, EFSA QPS-listed, non-GM, highly stable and suited to capsules and sachets